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Again, this does not include the gains from previous years. (Also of course, weight gain over time doesn't include weight gain during the first five years. For the final 5 years of the study they just kept their baseline weight and had weight fluctuation as the men aged, rather than weight gain.). This means that the men who followed the testosterone low dose and lost weight and gained weight over time have very low risk of excessive fat gain from testosterone therapy. The researchers also noted that the risk of excess weight gain over time was nearly non-existent in the low dose group. The risk was virtually non-existent even in those who gained excess weight within 5 years of starting treatment. The research also tells a story that is very similar to my comments and also the previous study: Low dosage testosterone therapy decreases the fatness of aging, while high dose testosterone (even with low dosages) increases fatness. The reason is that testosterone makes some fat cells less susceptible to being damaged by fat tissue, and also increases the number of fat cells per cell volume. Low dose testosterone therapy also makes the body fat more resistant to dieting. If it's true that testosterone helps normalize and improve body composition during aging, the fact that it can do this over time suggests that it helps in healthy aging itself and prevents other kinds of diseases. I have written in the past and will continue to write about other aspects of this research which are highly important. For example, if the testosterone therapy is not effective, men who get the wrong results have no reason to try the testosterone therapy again.
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